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18 A 2019 Cochrane review of eight RCTs of NAC alongside standard treatment versus standard treatment alone or standard treatment with placebo 41 found that when pooling data from all studies, the improvement in eradication rates failed to reach statistical significance, but when only data from those five RCTs that used current eradication regimens (triple therapy in four RCTs

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The Eab* of the sample supplemented with only AA was even higher than the control, whereas when sulfur dioxide was also present the Eab* was below 3 units

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