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The Pico Laser is safe and effective for all skin types, including darker skin tones, which are often more prone to hyperpigmentation

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Their common active ingredient, curcumin, can mediate mitophagy in OA chondrocytes by promoting AMPK/PINK1/Parkin, scavenging ROS, elevating mitochondrial membrane potential, and exerting an inhibitory effect on cartilage destruction (298)