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Its upregulation of antioxidant enzyme expression, including superoxide dismutase and catalase, has also been a subject of research interest

CB-1158 could block myeloid cell-mediated inhibition of T cell proliferation, increase the number of tumor-infiltrating CD8 + T cells and NK cells, and increase the expression of inflammatory factors and interferon-, thereby changing the immune microenvironment to promote inflammation and reduce tumor immune escape, inhibiting tumor cell proliferation

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10.3390/pharmaceutics14091890 89 QinY.GeG.YangP.WangL.QiaoY.PanG.et al (2023)