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More importantly, metformin monotherapy may be particularly beneficial for patients with PCOS in late childhood and early adolescence, as well as those who are averse to oral contraceptives

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Reprod Biol Endocrinol 8:20 Bertoldo MJ, Listijono DR, Ho WJ, Riepsamen AH, Goss DM, Richani D, Jin XL, Mahbub S, Campbell JM, Habibalahi A et al (2020a) NAD(+) repletion rescues female fertility during reproductive aging

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