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Preclinical research has also observed downregulation of pro-inflammatory cytokines including TNF-, IL-6, and IL-1, alongside modulation of NF-B signalling pathways positioning GHK-Cu as a subject of interest in inflammatory resolution research

Complex 2 , on the other hand, does not appear as a good model iron complex, because of the relative ease of ligand loss and interaction with GSH, even before plasma treatment

Luke MM, Kane JP, Liu DM, Rowland CM, Shiffman D, Cassano J, Catanese JJ, Pullinger CR, Leong DU, Arellano AR, Tong CH, Movsesyan I, Naya-Vigne J, Noordhof C, Feric NT, Malloy MJ, Topol EJ, Koschinsky ML, Devlin JJ, Ellis SG

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31 , e4287 (2022)