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Most significantly, Both PDA and Pt shell exhibit absorption in the Near-Infrared-II (NIR-II) region, which not only endow PDA@Pt with superior photothermal conversion efficiency for effective photothermal therapy (PTT) but also substantially enhances the nanomedicines capacity for UA degradation, O 2 production and ROS scavenging enzymatic activities

[3] Nevertheless, they are part of the ATP-grasp superfamily, which consists of 21 enzymes that contain an ATP-grasp fold

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The conversion of GSSG back to GSH depends on: adequate nutrients enzyme function liver health antioxidant support When this recycling system is overwhelmed, oxidized glutathione builds up and glow slows down

Acyl-coenzyme A synthetase long-chain family (ACSL) 4 and lysophosphatidylcholine acyltransferase 3 are critical for ferroptosis because they promote the activation and incorporation of PUFAs into membrane lipids