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4 Anti-inflammatory Properties : It exerts anti-inflammatory effects by modulating cytokine activity, which helps reduce local inflammation and associated pain

Simoens et al

This effect can last for several minutes and is believed to be driven by an accumulation of calcium ions in the presynaptic terminal

When these mast cells infiltrate the atrium, it induces PDGF-a (platelet-derived growth factor), which causes fibrosis in the mouse heart, causing a-fib