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& Chien, K

This review synthesizes evidence from peer-reviewed studies published between 2020 and 2026, focusing on mechanisms, efficacy, and safety

LL, JH, and QM contributed equally to this work

Chronic exposure has been associated with: Liver stress Immune suppression Increased inflammatory burden (14) Trichothecenes Often associated with Stachybotrys chartarum , trichothecenes can: Inhibit protein synthesis Disrupt mucosal immunity Intensify inflammatory signaling (15) Gliotoxin Produced by certain Aspergillus species, gliotoxin has immunosuppressive effects and may impair macrophage function and immune clearance (16)

Serotonin is one of the brains naturally occurring hormones