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Community reports suggest possible benefits, but essentially zero quality human trials exist

Aqueous phase of the cigarette smoke may undergo redox recycling for a period in the epithelial lining of the lungs [39]

This is consistent with GHK-Cus known role in upregulating collagen synthesis in dermal fibroblasts, a mechanism confirmed in a comprehensive review in Biomolecules documenting GHK-Cus influence across more than 4,000 human genes involved in tissue remodeling and repair

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