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Antiinflammatory, analgesic, and antiulcer activities of copper complexes suggest their use in a physiologic approach to treatment of arthritic diseases

et al., oral administration of Lactiplantibacillus plantarum Y15 to STZ + HFD-induced T2D mice improved fasting glucose, HbA1c, and HOMA-IR levels, reduced pro-inflammatory cytokines (IL-6, TNF-, among others), decreased the abundance of LPS-producing bacteria, and promoted SCFA-producing populations

Recent studies have underscored the complex regulation of GCL, particularly the role of GCLM in modulating GCLC activity and the enzymes sensitivity to feedback inhibition by GSH itself

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