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Cysteine is the rate-limiting step

32 Some studies have indeed shown that adding alginate-containing formulations to PPI therapy increases the response rate in patients with nonerosive reflux disease (NERD) as well as those with laryngopharyngeal reflux (LPR, for review see Scarpignato et al

Under metabolic stress, MOTS-c translocates from the cytoplasm to the nucleus, directly regulating gene expression related to stress adaptation

10.1128/JVI.02737-07

The stability of piroxicam, verapamil and 7-ethoxycoumarin were also determined and utilized as high, moderate and low metabolized controls, respectively