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Reference Module in Biomedical Sciences Teichman SL, Neale A, Lawrence B, Gagnon C, Castaigne JP, Frohman LA

Each element of the blood transport mechanism to the heart, when failing, sequentially causes blood stasis in the veins, the development of inflammation, damage to the endothelial layer lining the vessel, subsequently forming a thrombus that prevents blood transport to the heart

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In the UK, pernicious anaemia is typically treated with intramuscular hydroxocobalamin injections, though high-dose oral supplements may be considered in some cases under clinical supervision