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FIGURE 8 CARS CARS catalyzes the formation of cysteinyl aminoacyl-tRNA Cys (Cys-tRNA Cys ) through ATP-dependent activation of L-cysteine, yielding cysteinyl adenylate (Cys-AMP), followed by transfer of cysteine to the 3-terminus of tRNA Cys (Newberry et al., 2002

doi: 10.1016/j.ces.2021.117129 121

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The TMEM192-mKeima probe specifically assays lysophagy and reveals its initial steps

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