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Administration of 3-hydroxyanthranilic acid (3-HAA), a downstream tryptophan metabolite, ameliorated the symptoms of EAE by increasing the number of Treg cells and inhibiting the functions of Th1/Th17 cells (82)

Patients can receive vaccinations while being treated with DMF and most surgical interventions do not necessitate FAE discontinuation, other than those on the gastrointestinal system (as DMF is metabolised by gut esterases)

Richardson SM, Hughes N, Hunt JA, Freemont AJ, Hoyland JA: Human mesenchymal stem cell differentiation to NP-like cells in chitosan-glycerophosphate hydrogels

& Gilliatt, R

Not only does this damage the protein molecules, but it also stimulates inflammatory processes throughout the body