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Potential participants were excluded if they reported diagnosed chronic disease, regular supplementation with curcumin/turmeric and/or pomegranate and/or MSM, habitual intake of pain relievers (i.e., ibuprofen, acetaminophen, aspirin), and/or contraindications to exercise

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In sheep, late-gestation pregnancy toxemia is defined as a nutrition-related metabolic disorder resulting from disruptions in carbohydrate and fatty acid metabolism (Rook, 2000

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Regulation of T cell metabolism by immunosuppressive signals in the TME Immunosuppressive signals in the TME severely disrupt the oxidative metabolism of T cells, preventing them from meeting the metabolic demands of their effector functions (Fig