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Despite scarce data in relation to oxidative damage in children suffering from konzo, the role of oxidative damage in many other neurologic diseases has been well established 37

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Comhair SA, Thomassen MJ, Erzurum SC: Differential induction of extracellular glutathione peroxidase and nitric oxide synthase 2 in airways of healthy individuals exposed to 100% O(2) or cigarette smoke

Thus, even though AhpF can obtain electrons from NADH, based on the relatively low availability of NADH in cells, the suppressor mutant of AhpC is likely fueled predominantly by NADPH