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Cycling: 4-week cycles followed by 4-8 week breaks allow assessment of lasting effects and prevent potential receptor adaptations

Critical challenges included insufficient sample size reducing statistical power, reliance on self-reported exposure data introducing recall bias, and inadequate control for confounding factors such as smoking and alcohol consumption

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If combining with an active treatment, timing recommendations should come from your provider

doi: 10.1155/2017/8074329 103 CulemannSKnabKEulerMWegnerAGaribagaogluHAckermannJet al