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For women specifically, this gap is even larger given the superior female response to triple agonism documented in the Phase 2 data

GTP-bound RhoA activates ROK, which phosphorylates and thereby inhibits MLCP, enhancing MLC phosphorylation mediated by myosin light chain kinase (MLCK), and ultimately promoting smooth muscle contraction (Kimura et al., 1996)

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Las cpsulas son del tamao adecuado y se deslizan con facilidad al ser ingeridas, lo que resulta especialmente conveniente para quienes tienen un estilo de vida activo o apurado

2009 Feb 21;15(7):804-16