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Loss of muscle function due to declining muscle mass and quality is a hallmark of cancer cachexia, a complex syndrome that severely compromises patients' quality of life and survival

[2] This stability may support sustained biological activity across laboratory settings in which many shorter synthetic peptides would undergo rapid proteolytic degradation

Taylor HR, West SK, Rosenthal FS, et al

To understand the underlying mechanisms, inhibitors targeting the Notch pathway (DAPT) and NF-B pathway (BMS) were also applied to HUVEC and murine CLI models