l carnitine fat metabolism L-Carnitine | Linus Pauling Institute Carnitine Metabolism and Its Role

Cell transfection Cells were transfected with pcDNA 3.1 overexpression vectors (pcDNA 3.1-YTHDF1 and pcDNA 3.1-SLC7A5, with the empty pcDNA 3.1 vector as a negative control) and siRNAs (Invitrogen) targeting YTHDF1 and SLC7A5 (si-YTHDF1, si-SLC7A5, with non-targeting siRNA (si-NC) as a negative control)

The polymorphism in GSTM1 and GSTT1 genes, leads to complete lack of activity of their corresponding enzymes and is responsible for poor elimination of carcinogenic substances which are potential sources of reactive oxygen species (Rebbeck, 1997

See results in just 7-28 days

Guillon, O., Rheinheimer, W

2021;16: e0245986