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The underlying mechanism may be related to a key modulator of neutrophil maturation, granulocyte-macrophage colony-stimulating factor (GM-CSF), which was observed to be higher in young adult females than males, followed by diminishing after menopause (53)

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BPC-157 may also upregulate the expression of early growth response gene-1 (EGR-1), which is a growth factor with potential benefits for the nervous system, having been suggested to aid in early extracellular matrix (collagen) formation [5]