For instance, supplementation with BCAAs can alleviate gut microbial dysbiosis, improving amino acid metabolism and host growth performance [79]
These effects could be ascribed to the antioxidant and free radical scavenging properties of both SE and AST, which is probably mediated, via donating electrons to free radicals, thus stabilizing them and changing them into inactive form , together with their ability to enhance antioxidant defense mechanisms (Gutirrez-del-Ro et al
By elevating NAD+ and activating SIRT1, 5-Amino-1MQ promotes the proliferation and differentiation of muscle stem cells into fusion-competent myoblasts, facilitating effective muscle repair and regeneration
Second, the glutathione S-transferases (GSTs) catalyze the conjugation of the thiol group of GSH to a vast array of electrophilic xenobiotics and endogenous metabolites
Recent studies confirm the presence of ferroptosis in HS and highlight key targets regulating this process (Figures 2C, D