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How the disruption of mitochondrial redox signalling contributes to ageing

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In people without ADHD a meta-analysis of 48 placebo-controlled trials found only small effects on inhibitory control and memory, and its authors noted that much of what healthy users feel may be improved energy and motivation rather than faster thinking

SIRT3 (widely expressed in mitochondria-rich tissues such as kidney, heart, brain, and liver tissue), is linked to age-related diseases, cancer, and heart and metabolic diseases, suggesting that it may be a potential therapeutic target [144]