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A 2026 UK evidence review of the estrogen-BDNF-HGF axis, HRT first, and realistic expectations

Alpha-lipoic acid (ALA) is involved in energy production, blood sugar control, brain health and detoxification

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In the SCALE Obesity and Prediabetes trial, 61% of participants had prediabetes 17 , while the prevalence of baseline prediabetes was not stated for the SCALE Maintenance 16,17 and SCALE IBT 15 trials, and participants mean HbA1c was 5.5%

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