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Rita Nogueira-Ferreira acknowledges FCT for the research contract CEECIND/03935/2021 under the CEEC Individual 2021 ( Ethics declarations Conflicts of interest The authors declare no competing interests

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Now, this PI3K phosphorylates phosphatidylinositol 4, 5-diphosphate (PIP2), which is converted into phosphatidylinositol-3,4,5-trisphosphate (PIP3) by further phosphorylation and activation by phosphoinositide-dependent protein kinase-1 (PDPK-1)

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Antioxidants 11(6):1128