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It can do this by reducing the expression of hTERT mRNA, but also by its - anti-estrogenic capacity

NAD+ is a key molecule involved in all aspects of metabolism, energy production in cells

The Ransod assay (RANDOX Laboratories, Crumlin, UK) was used to quantify the activity of superoxide dismutase (SOD), which is an antioxidant enzyme that protects cells against the pro-oxidant action of superoxide free radicals

a family of kinases activated in response to stress and inflammatory stimuli that modulates multiple aspects of cardiac fibroblast function, including inflammatory responses, myofibroblast differentiation, extracellular matrix turnover and the paracrine induction of cardiomyocyte hypertrophy (Turner and Blythe, 2019)