Through chemical modification of the lysine side chain or backbone, molecules can be endowed with entirely new physicochemical properties and biological activities
The arrhythmias persisted on Day 0 and after 24-hour incubation in fresh medium (Day 1)
doi: 10.3389/fmicb.2024.1446595 Received 10 June 2024 Accepted 02 August 2024 Published 14 August 2024 Volume 15 - 2024 Edited by Daniela De Biase, Sapienza University of Rome, Italy Reviewed by Wolfgang Buckel, University of Marburg, Germany Malte Sinn, University of Konstanz, Germany Updates Copyright 2024 Piskol, Lukat, Kaufhold, Heger, Blankenfeldt, Jahn and Moser
TCF4 knockdown can promote ferroptosis and increase the cisplatin sensitivity of gastric cancer cells, 197 suggesting that abnormal activation of Wnt/-catenin pathway increases ferroptosis resistance in gastric cancer cells, offering a possible therapeutic strategy for enhancing chemotherapy sensitivity in patients with advanced gastric cancer
Notably, expression of malic enzyme 1 (ME1), a cytosolic enzyme generated from malate, was elevated (Supplementary Fig