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Deficiency of glutathione puts the cell at risk for oxidative damage

In particular, low micromolar to millimolar concentrations of Trolox are used in cell culture and in vivo applications ( Figure 5A , AX preincubation with PBS or Trolox did not significantly reduce AX-HSA adduct formation with respect to the adducts formed by the freshly prepared mixtures, whereas preincubation with TCEP showed a tendency towards decreasing adduct levels

Rango M, Bresolin N (2018) Brain mitochondria, aging, and Parkinsons disease

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