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In support of this, treatment of AALF mice with IL-10 neutralizing antibody increased monocyte numbers in the liver ( Figure 8A ), which coincided with a decrease in the area of necrosis, suggesting that the recovery of monocyte recruitment restored, in part, dead cell clearance ( Figures 9A, B )

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O 2 stimulates oxidation through various mechanisms such as the reduction of transition metals, the induction of metal release from proteins, forming conjugated acids in a pH-dependent manner and spontaneously dismutating itself into hydrogen peroxide [9]