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Plant J 29:257268 Mhamdi A, Mauve C, Gouia H, Saindrenan P, Hodges M, Noctor G (2010) Cytosolic NADP-dependent isocitrate dehydrogenase contributes to redox homeostasis and the regulation of pathogen responses in Arabidopsis leaves

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This is the reason why its beneficial to your weight management, but it also means that: Your daily calorie intake can be lower The energy you have may be reduced You may feel a temporary weakness or fatigue Blood Sugar Fluctuations Another reason why you feel so tired is because of the changes in your blood sugar level

For instance, in a proteomics lab, peptides used in mass spectrometry might be stored in the fridge between experimental runs