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Study 6: Lutz 2010, basic mechanism Citation: Lutz T.A

Discussion To identify emerging senolytics, we screened a library of electrophilic compounds, which can target proteins through covalent bond formation

Even a highly purified peptide can produce inconsistent experimental results if it is improperly reconstituted, contaminated during handling, or stored outside recommended conditions

Whilst studies in humans have demonstrated that patients with asthma exhibit dysregulated rhythms in serum melatonin concentrations, the pathological mechanisms precipitated by this remain poorly understood (15)

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