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This peptide was first isolated and identified in the 1990s by Croatian researchers, who observed its remarkable protective properties on gastrointestinal tract tissues

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Activation of oncogenes and loss of tumor suppressors lead to the increased production of superoxide via mitochondria and NADPH oxidase (NOX) pathways ( 2 O 2 ), a more stable and stronger oxidizing molecule, through the action of superoxide dismutase enzymes (SOD)

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