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These findings may inform appropriate expectation setting for patients and clinicians and highlight the need for better methods of treatment selection for patients with degenerative lumbar spinal stenosis. Surgery caused adjacent segment disease A December 2025 study ( 20 ) explained that lateral lumbar interbody fusion (LLIF) works by indirectly providing decompression by restoring disc height

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Elevated MCT4 expression is associated with impaired neurite growth and increased apoptosis ( Studies show that MCTs promote the uptake of extracellular lactate by macrophages, leading to lactylation of HMGB1

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