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doi: 10.3389/fphys.2024.1504978 Received 01 October 2024 Accepted 17 December 2024 Published 09 January 2025 Volume 15 - 2024 Edited by Ahmad Alkhatib, Birmingham City University, United Kingdom Reviewed by M

12511141) and Harbin normal university (HSDSSCX2018-20)

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In this context, Du et al., noted loss of tissue resident macrophages in colon biopsies from patients with ulcerative colitis, that was accompanied by decreased superoxide dismutase 2 expression (an important antioxidant) in the macrophages [3]