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Higher concentrations of glycochenodeoxycholic acid, glycodeoxycholic acid, hyodeoxycholic acid, and certain bile acid ratios were associated with patient CSF tau and p-tau

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Some patients have been described in whom SLE coexists with WD [200,201,202,203,204,205,206,207,208,209] (see Table 4)

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First, while the rescue experiments with ferric citrate and NAC strongly support an iron deficiency and ROS-mediated mechanism, the absence of established positive controls, such as the iron chelator deferoxamine (DFO) or direct ROS generators, precludes a definitive comparative conclusion that the observed effects are uniquely attributable to CGAs iron-chelating activity