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The Italian Society on Alcohol has, therefore, implemented a task force of specialists to draw up recommendations for the treatment of AWS with the following main results: (1) while mild AWS may not require treatment, moderate and severe AWS need to be pharmacologically treated

Antioxidant Protection: Helps defend against environmental aggressors and pollutants

Catechin hydrate directly inhibits macrophage RasGRP1, a pro-inflammatory gene in macrophages, thereby diminishing excessive inflammation and oxidative stress that contribute to numerous organ dysfunctions resulting from sepsis (278)

This effect is particularly relevant in tissues like brown and beige adipose tissue, where ERRs regulate thermogenic programs including uncoupling protein 1 (UCP1) expression

doi: 10.3945/an.115.010322 16