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They found that in addition to slowing the progression of degeneration in the treatment group compared to controls, the peptide also improved levels of the protein aggrecan

Moreover, microglial cells are least vulnerable to ischemia because they express glutamate receptors only after the onset of pathological conditions when they become reactive (Gottlieb and Matute, 1997)

However, its specificity for the fibrotic pathology of frozen shoulder makes it an important peptide to watch in this space

Yang Y, Sheng L, Hang X, Wang J, Kou G, Ye Y, Ji J, Sun X (2025) Efficient expression and activity optimization of manganese peroxidase for the simultaneous degradation of aflatoxins AFB(1), AFB(2), AFG(1), and AFG(2)

Relative mRNA levels were measured by qRT-PCR relative to the internal ACT1 mRNA control