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Description

The supply pathway involves the export of GSH from astrocytes via the multidrugresistance protein 1 (Mrp1), extracellular processing of GSH by astrocytic glutamyl transpeptidase (GT) to the dipeptide cysteinylglycine (CysGly) and hydrolysis of this dipeptide by neuronal aminopeptidase N (ApN) to cysteine (Cys) and glycine (Gly)

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10.1101/cshperspect.a026252 110 SinghG.LeH.AblordeppeyK.LongS.MinochaR.DhankherO

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doi: 10.1186/s40814-023-01235-z Summary Keywords depressive disorder, gut microbiota, gut-brain axis (GBA), dysbiosis, metabolites, probiotics, prebiotics, FMT Citation Luqman A, He M, Hassan A, Ullah M, Zhang L, Rashid Khan M, Din AU, Ullah K, Wang W and Wang G (2024) Mood and microbes: a comprehensive review of intestinal microbiotas impact on depression

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