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Its regulatory network remains incompletely mapped, as it involves numerous overlapping and often contradictory signaling pathways
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Both models excluding the subjects with ESRD occurring within 3 years (adjusted HR 1.989, 95% CI 1.7462.256) and 5 years (adjusted HR 1.944, 95% CI 1.6232.328) demonstrated a significant association between RA and the risk of ESRD, suggesting the least likelihood of reverse causation
By releasing Fe 3+ and tannic acid in melanoma cells, TPL@TFBF initiated Fenton reactions for lipid peroxidation (ferroptosis) while activating gasdermin D-mediated pyroptosis
Even at a high concentration of 320 g/mL, the hemolysis rate of PDA@Pt was only 3.2%, demonstrating the excellent safety profile of the nanodrug (Fig
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