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However, no significant difference in serum MT-1 levels was observed among inactive gout patients, healthy individuals, and those with HUA without gout

3.2 Bidirectional regulation of lipid metabolism Lipid metabolism serves as a critical bidirectional regulator of CD4 + T cell differentiation, dynamically shaping the balance between pro-inflammatory Th17 cells and immunoregulatory Treg cells through integrated control of extracellular lipid uptake, intracellular synthesis, and FAO (90, 91)