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Complex environment experience rescues impaired neurogenesis, enhances synaptic plasticity, and attenuates neuropathology in familial Alzheimer's disease-linked APPswe/PS1DeltaE9 mice

Castelnovo et al., 2017), apart from quiescent myelinating or nonmyelinating entities, the Schwann cells represent a very heterogenous population, which can rapidly trans or dedifferentiate into repair, bridge, phagocytic or mesenchymallike phenotypes in the case of nervous system injury (see also Figures 24), thus guiding the regrowing axons (Jessen and Mirsky, 2016) to their destination

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Samples show the histological characteristics of normal gingivomucosal sections