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31,32 In diabetic peripheral neuropathy (DPN), macrophages infiltrate to initiate repairment on nerve injury, with more cytokine and chemokine released
10.1016/j.jaci.2005.12.1331 101 GuH.AnH.-J.KimJ.-Y.KimW.-H.GwonM.-G.KimH.-J.et al (2019)
Moreover, using conditional knockout mouse models (e.g., chondrocyte-specific Trpv1 / or Slc2a1 / ), the protective effects of CAT on ferroptosis and OA progression in vivo need to be verified, combined with spatial metabolomics to analyze dynamic changes in lipid peroxidation products and antioxidant molecules in joint tissues following CAT intervention
Although the anti-inflammatory effects of the CB 2 R are well-characterized, it is also important to note that the CB 2 R seems essential for many environmental-induced immune responses in microglia
Takebayashi A, Kimura F, Kishi Y, Ishida M, Takahashi A, Yamanaka A, et al
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