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These combine monothiophosphate-backbone-substituted aptamers for enhanced stability and protein binding with chemically modified uridine (referred to as X) that allows drug-like compounds or additional functionalities to be attached to the aptamers

It is a comparison between two formulations of the same active compound, each with distinct advantages depending on the intended route of administration and therapeutic goals

Highly expressed EGFR contributes towards regional lymph node metastasis and poor outcomes

Chaudhry, K., Tafti, D

In silico modelling suggests that rs146558 is a nonsynonymous single nucleotide polymorphism that leads to disruption in protein function