Nutritional intervention as a complementary neuroprotective approach against propionic acid-induced neurotoxicity and associated biochemical autistic features in rat pups
Considering the evidence addressing the ameliorating effects of either L-carnitine or biotics on metabolic indices, also the reports addressing higher efficacy of concomitant supplementation versus single-therapies, this clinical trial was conducted to assess the effects of L-carnitine + multi-species/multi-strain synbiotic combined supplementation compared to L-carnitine mono-therapy on atherogenic-indices, body composition, visceral obesity, and appetite sensations in 46 metabolically healthy women with obesity, randomly assigned to co-supplementation (L-carnitine-tartrate (2 500 mg/dl) + synbiotic (one capsule/day)) or mono-therapy (L-carnitine-tartrate (2 500 mg/dl) + maltodextrin (one capsule/day)) groups for 8 weeks
Int J Mol Sci 22(6):3101
Another challenge lies in the translation of optimized formulations across food matrices: a nanoemulsion stable in an aqueous drink may destabilize in an emulsion-rich dairy product, highlighting the need for matrix-specific revalidation (196)
Ingredientes Cereza Agua potable, L-carnitina 20%, acidulante (cido ctrico), inulina, aroma, nicotinamida, conservadores (cido srbico, benzoato de sodio), D-pantotenato clcico, extracto de hoja de t verde ( Camellia sinensis ) 0,05%, clorhidrato de piridoxina, edulcorantes (acesulfamo K, sucralosa), clorhidrato de tiamina, colorantes (azorrubina 1 , azul brillante FCF)