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Similar results for Chinese hamsters exposed by the inhalation route to 28 -36 mg/m 3 for 16 h (males only), or by a single oral dose of 15 mg/kg body weight (males) or 10 mg/kg body weight (females), have been reported (Dean & Thorpe, 1972a)

doi: 10.1002/jnr.24357 134 Ul HaqS.KhanA.AliM.KhattakA

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Other van der Waals interactions observed in IgA between Fc and -hairpin 2 are absent in IgM between Fc and -hairpin 2 31 , which could explain the higher flexibility of -hairpin 2 in IgM in comparison to IgA (Supplementary Fig