These proteins, acting as cyclin-dependent kinase (Cdk) inhibitors, lead to the arrest of the G1 phase, and activation of the senescence pathway [90]
Liu, Y., et al., Alpha-lipoic acid improves high-fat diet-induced hepatic steatosis by modulating the transcription factors SREBP-1, FoxO1 and Nrf2 via the SIRT1/LKB1/AMPK pathway
Possible side effects may include injection site pain, redness, swelling, allergic reactions, nausea, or dizziness
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In addition, IF has been shown to modulate the limbic dopaminergic and thyrotropin-releasing hormone (TRH) systems, which regulate feeding behavior and hypothalamic-pituitary-thyroid (HPT) axis activity [62]