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Their use is not prohibited by WADA, however some sporting authorities ban the use of hypoxic chambers during competitions under their sport rules

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The most commonly used intramuscular injection sites include: Avoiding incorrect injections requires a combination of proper training, site selection, and adherence to medical guidelines

Community sources variously attribute it to dose, to the DMSO carrier in transdermal use, or to vascular effects, with no way to confirm cause in self-reports