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Shelf Life: Use reconstituted solutions within 30 days of mixing to ensure compound stability

Pernicious anaemia , the autoimmune condition causing B12 malabsorption, may coexist with other autoimmune disorders, including autoimmune thyroid disease and, less commonly, rheumatoid arthritis

A recent systematic review and meta-analysis of 25 observational studies found proton-pump inhibitor use was associated with a small increased risk of vitamin B 12 deficiency

Cofactors are a lot like this as they help the processes of the body run smoothly and B12 is a cofactor in many of these processes