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The ECM provides structural support to tissues and consists primarily of: collagen elastin glycosaminoglycans GHK-Cu appears to influence this matrix in several ways: stimulating collagen types I and III synthesis promoting elastin production enhancing glycosaminoglycan formation reducing enzymes that degrade collagen Together, these processes help maintain skin elasticity, structural integrity, and resilience
How DSIP might act in the body DSIP is discussed as a brain-active peptide, but its exact receptor picture is still unclear

Timestamps (00:00:00) Optimizing Neurochemicals to Improve Health (00:03:40) Momentous Supplements (00:05:30) Sleep & Maintaining Healthy Metabolism (00:09:52) Tools: How to Wake Up Earlier, Night Owls (00:19:32) AG1 (Athletic Greens), Thesis, InsideTracker (00:22:05) Nervous System Overview (00:31:32) How Neuromodulators Work (00:34:24) Baseline Neuromodulator Levels, 3 Daily Phases (00:42:15) Hormones Modulate Neuromodulators (00:52:12) The 4 Major Types of Neuromodulators (01:01:45) Tool Kit 1: Increase Baseline Dopamine & Focus (01:08:52) Tyrosine-rich Foods & Dopamine (01:10:59) Dopamine Supplementation: Mucuna Pruriens, L-tyrosine & Phenylethylamine (01:16:00) Deliberate Cold Exposure & Dopamine (01:21:12) Tool Kit 2: Additional Tips to Increase Dopamine (01:26:10) Tool Kit 3: Increase Epinephrine (Adrenaline) & Alertness (01:34:34) Tool Kit 4: Increase Acetylcholine & Attention/Learning

Since the introduction of bromide as an anti-seizure drug in 1857, there has been an impressive expansion of clinically effective therapies in decreasing the frequency and severity of seizures in people with epilepsy