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PMID 22411236

phosphorylated MLKL aggregates and inserts into the cell membrane, disrupting membrane integrity, causing cell swelling, plasma membrane rupture, and content leakage, ultimately presenting a necrotic morphology [44]

10.1001/jamainternmed.2019.6969 JAMA Intern Med

Reinforces cartilage integrity, connective tissue metabolism, and inflammatory balance

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